3037947-20-6
Chemical Structure
EGFR-IN-74
- CAS No.: 3037947-20-6
- Formula:C32H28BrF3N6O4S
- Molecular Weight:729.57
IUPAC Name: (R)-3-aminopyrrolidine-2,5-dione
InChIKey: NTWIRWVNYBTFDJ-UHFFFAOYSA-N
SMILES: CCOC(C1=C(C2=CC(Br)=CC=C2N=C1N3C=CN=C3)N4CCN(CC4)C5=C(C=CC=C5)NS(=O)(C6=CC=C(C=C6)C(F)(F)F)=O)=O
Biological Activity: EGFR-IN-74 (Compound 21) is a potent EGFR inhibitor with an IC50 of 138 nM against EGFR L858R/T790M. EGFR-IN-74 induces cancer cell apoptosis[1].
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EGFR-IN-74 | EGFR-IN-74 (Compound 21) is a potent EGFR inhibitor with an IC50 of 138 nM against EGFR L858R/T790M. EGFR-IN-74 induces cancer cell apoptosis. | |||||||||||||||||||||
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Keywords