3037947-20-6

EGFR-IN-74 Chemical Structure
3037947-20-6

Chemical Structure

EGFR-IN-74

  • CAS No.: 3037947-20-6
  • Formula:C32H28BrF3N6O4S
  • Molecular Weight:729.57

IUPAC Name: (R)-3-aminopyrrolidine-2,5-dione

InChIKey: NTWIRWVNYBTFDJ-UHFFFAOYSA-N

SMILES: CCOC(C1=C(C2=CC(Br)=CC=C2N=C1N3C=CN=C3)N4CCN(CC4)C5=C(C=CC=C5)NS(=O)(C6=CC=C(C=C6)C(F)(F)F)=O)=O

Biological Activity: EGFR-IN-74 (Compound 21) is a potent EGFR inhibitor with an IC50 of 138 nM against EGFR L858R/T790M. EGFR-IN-74 induces cancer cell apoptosis[1].

Cat. No. Product Name Purity Description Pricing
HY-151981
EGFR-IN-74 EGFR-IN-74 (Compound 21) is a potent EGFR inhibitor with an IC50 of 138 nM against EGFR L858R/T790M. EGFR-IN-74 induces cancer cell apoptosis.
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