3040120-35-9
Chemical Structure
Neuraminidase-IN-20
- CAS No.: 3040120-35-9
- Formula:C21H18FN3O2S
- Molecular Weight:395.45
InChIKey: NXLRKVVIWYJNMG-ZVHZXABRSA-N
SMILES: C/C(C1=CC=C(C=C1)NC(CC2=CC=CS2)=O)=N\NC(C3=CC=C(C=C3)F)=O
Biological Activity: Neuraminidase-IN-20 (Compound 5i) is a potent inhibitor of mutant neuraminidase (NA) (H5N1-H274Y) (IC50= 0.44 μM).Neuraminidase-IN-20 binds to the 430 cavity site of NA and disrupts the enzymatic activity of NA[1].
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Neuraminidase-IN-20 | Neuraminidase-IN-20 (Compound 5i) is a potent inhibitor of mutant neuraminidase (NA) (H5N1-H274Y) (IC50= 0.44 μM).Neuraminidase-IN-20 binds to the 430 cavity site of NA and disrupts the enzymatic activity of NA. | |||||||||||||||||||||
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Keywords