3041072-11-8
3041072-11-8
Chemical Structure
Sigma-1 receptor antagonist 4
- CAS No.: 3041072-11-8
- Formula:C22H26N2O
- Molecular Weight:334.45
IUPAC Name: 6-phenyl-2-(3-(p-tolyl)propyl)-2,6-diazaspiro[3.4]octan-7-one
InChIKey: XRKKADYYRPDJSD-UHFFFAOYSA-N
SMILES: CC1=CC=C(C=C1)CCCN2CC3(C2)CC(N(C3)C4=CC=CC=C4)=O
Biological Activity: Sigma-1 receptor antagonist 4 (Compound 32) is a potent σ1R antagonist that significantly enhances the analgesic effect of morphine and rescues morphine-induced analgesic tolerance, with potential to prevent morphine tolerance[1].
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Sigma-1 receptor antagonist 4 | Sigma-1 receptor antagonist 4 (Compound 32) is a potent σ1R antagonist that significantly enhances the analgesic effect of morphine and rescues morphine-induced analgesic tolerance, with potential to prevent morphine tolerance. | |||||||||||||||||||||
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