3049405-60-6
3049405-60-6
Chemical Structure
COX-2-IN-33
- CAS No.: 3049405-60-6
- Formula:C20H13ClF3N5O4
- Molecular Weight:479.80
InChIKey: CRMFBTQUPQALSY-UHFFFAOYSA-N
SMILES: O=C(OCC1=[N+]([O-])ON=C1C2=CC=CC=C2)C3=NN(C4=CC=CC(C(F)(F)F)=C4)C(CCl)=N3
Biological Activity: COX-2-IN-33 (compound 5f) is a COX-2 inhibitor (IC50=45.5 nM), as well as a potential anti-inflammatory agent. COX-2-IN-33 inhibits in vivo pro-inflammatory cytokine production and keep gastric safety[1].
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COX-2-IN-33 | COX-2-IN-33 (compound 5f) is a COX-2 inhibitor (IC50=45.5 nM), as well as a potential anti-inflammatory agent. COX-2-IN-33 inhibits in vivo pro-inflammatory cytokine production and keep gastric safety. | |||||||||||||||||||||
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References
Keywords
