3052352-22-1
3052352-22-1
Chemical Structure
DMU759
- CAS No.: 3052352-22-1
- Formula:C15H16F3N3S
- Molecular Weight:327.37
IUPAC Name: 7-(cyclohexylthio)-5,6,8-trifluoro-2-methylquinazolin-4-amine
InChIKey: CUXWPADNJJSWHY-UHFFFAOYSA-N
SMILES: NC1=C2C(F)=C(F)C(SC3CCCCC3)=C(F)C2=NC(C)=N1
Biological Activity: DMU759 is a Lysyl-tRNA synthetase 1 (KRS1) inhibitor. DMU759 has potent anti-kinetoplastid activity against Trypanosoma cruzi , Trypanosoma brucei and Leishmania donovani. DMU759 significantly reduces parasitemia in acute Chagas disease mice model. DMU759 can be used for parasitic infection like Chagas disease research[1].
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DMU759 | DMU759 is a Lysyl-tRNA synthetase 1 (KRS1) inhibitor. DMU759 has potent anti-kinetoplastid activity against Trypanosoma cruzi , Trypanosoma brucei and Leishmania donovani. DMU759 significantly reduces parasitemia in acute Chagas disease mice model. DMU759 can be used for parasitic infection like Chagas disease research. | |||||||||||||||||||||
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References
Keywords
