3052742-91-0
3052742-91-0
Chemical Structure
RIPK2/3-IN-1
- CAS No.: 3052742-91-0
- Formula:C24H16N4O2S2
- Molecular Weight:456.54
InChIKey: OUMWMQOMQTXCGS-UHFFFAOYSA-N
SMILES: OCC1=CC=C(O1)C2=CC3=C(C=C2C4=CC=CS4)C(NC5=CC(N=CS6)=C6C=C5)=NC=N3
Biological Activity: RIPK2/3-IN-1 is a potent dual RIPK2/3 kinases inhibitor with IC50 values of 3 nM and 117 nM, respectively. RIPK2/3-IN-1 is against RIPK2 with IC50 value 14 nM in 14-TriLAN-Gly/NOD1 THP-1 cell-based NF-κB reporter assay[1].
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RIPK2/3-IN-1 | RIPK2/3-IN-1 is a potent dual RIPK2/3 kinases inhibitor with IC50 values of 3 nM and 117 nM, respectively. RIPK2/3-IN-1 is against RIPK2 with IC50 value 14 nM in 14-TriLAN-Gly/NOD1 THP-1 cell-based NF-κB reporter assay. | |||||||||||||||||||||
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References
Keywords
