3052814-78-2
Chemical Structure
Anti-inflammatory agent 53
- CAS No.: 3052814-78-2
- Formula:C24H22N2O4S
- Molecular Weight:434.51
InChIKey: DXXMSZOJVSSAQM-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(OC)C=C1)COC2=CC=C(N3C(C4=CC=CC=C4)SCC3=O)C=C2
Biological Activity: Anti-inflammatory agent 53 (compound 7c) is an orally active selective COX-2 inhibitor. Anti-inflammatory agent 52 has anti-HT29 transfer activity, which leads to periodic arrest in S phase and G2/M phase. Anti-inflammatory agent 52 has safety, moderate ability to suppress inflammation. Anti-inflammatory agent 52 has a rare property of suppressing the development of tumor in mouse model, showing anti-cancer activity[1].
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Anti-inflammatory agent 53 | Anti-inflammatory agent 53 (compound 7c) is an orally active selective COX-2 inhibitor. Anti-inflammatory agent 52 has anti-HT29 transfer activity, which leads to periodic arrest in S phase and G2/M phase. Anti-inflammatory agent 52 has safety, moderate ability to suppress inflammation. Anti-inflammatory agent 52 has a rare property of suppressing the development of tumor in mouse model, showing anti-cancer activity. | |||||||||||||||||||||
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Keywords
