3053482-15-5

AT1R antagonist 3 Chemical Structure
3053482-15-5

Chemical Structure

AT1R antagonist 3

  • CAS No.: 3053482-15-5
  • Formula:C22H16N6O2S
  • Molecular Weight:428.47

InChIKey: VCNVPSWWGLXSSO-UHFFFAOYSA-N

SMILES: O=C(C1=CC2=C(NC(SCC3=CC=C(C=C3)C4=C(C=CC=C4)C5=NN=NN5)=N2)C=C1)O

Biological Activity: AT1R antagonist 3 (Compound 1) is an antagonist for angiotensin II type 1 receptor (AT1R) and an inhibitor for calcium channel type-L CaV1.2 (IC50=0.57 μM). AT1R antagonist 3 exhibits vasodilation efficacy in solated rat aorta (10 μM, 88.7%) and antihypertensive efficacy in rat models[1].

Cat. No. Product Name Purity Description Pricing
HY-159090 		AT1R antagonist 3 AT1R antagonist 3 (Compound 1) is an antagonist for angiotensin II type 1 receptor (AT1R) and an inhibitor for calcium channel type-L CaV1.2 (IC50=0.57 μM). AT1R antagonist 3 exhibits vasodilation efficacy in solated rat aorta (10 μM, 88.7%) and antihypertensive efficacy in rat models.
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