3056857-07-6
3056857-07-6
Chemical Structure
YL-5092
- CAS No.: 3056857-07-6
- Formula:C22H14F3N3O2S
- Molecular Weight:441.43
InChIKey: HLKQNAGWYQKBSH-UHFFFAOYSA-N
SMILES: O=C(C1=CNC(C(NC2=CC=C(C3=CN=CS3)C=C2)=O)=C1)C4=C(C(F)(F)F)C=CC=C4
Biological Activity: YL-5092 is a selective YT521-B homology (YTH) domain-containing protein 1 (YTHDC1) inhibitor with an IC50 of 7.4 nM and a KD of 29.6 nM. YL-5092 can suppress cancer cell proliferation and induce cell G0/G1 phase arrest and apoptosis. YL-5092 can be used for the research of cancer, such as acute myeloid leukemia (AML)[1].
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YL-5092 | 99.83% | YL-5092 is a selective YT521-B homology (YTH) domain-containing protein 1 (YTHDC1) inhibitor with an IC50 of 7.4 nM and a KD of 29.6 nM. YL-5092 can suppress cancer cell proliferation and induce cell G0/G1 phase arrest and apoptosis. YL-5092 can be used for the research of cancer, such as acute myeloid leukemia (AML). | ||||||||||||||||||||
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References
Keywords
