3058605-06-1
3058605-06-1
Chemical Structure
TB114
- CAS No.: 3058605-06-1
- Formula:C32H33Cl2N3O4
- Molecular Weight:594.53
InChIKey: SGPRGPKOFWSIJK-PJGOFDOSSA-N
SMILES: ClC1=CC([C@@H]2[C@@]3(C4=CC=C(Cl)C=C4NC3)[C@H](CC(C)(C)C)N5[C@H]2C(N(C5)C6=C(OC)C=C(C(O)=O)C=C6)=O)=CC=C1
Biological Activity: MDM2-IN-27 targets MDM2 protein (Ki = 0.4 nM). MDM2-IN-27 activates the anti-tumor activity of p53 and induces apoptosis by blocking the negative regulation of p53 by MDM2[1].
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TB114 | MDM2-IN-27 targets MDM2 protein (Ki = 0.4 nM). MDM2-IN-27 activates the anti-tumor activity of p53 and induces apoptosis by blocking the negative regulation of p53 by MDM2. | |||||||||||||||||||||
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References
Keywords
