3065081-87-7
Chemical Structure
PRMT5-IN-47
- CAS No.: 3065081-87-7
- Formula:C24H22FN5O2
- Molecular Weight:431.46
SMILES: NC1=NC2=C(C=C(C(F)=C2)C(N(C)[C@H]3CN(CC3)C4=CC=C(C=C4)C#N)=O)C5=C1COC5
Biological Activity: PRMT5-IN-47 (compound 20) is a potent, selectively and orally active, MTA cooperative PRMT5 inhibitor with an IC50 value of 15 nM. PRMT5-IN-47 shows antiproliferative activity. PRMT5-IN-47 shows anticancer activity[1].
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PRMT5-IN-47 | PRMT5-IN-47 (compound 20) is a potent, selectively and orally active, MTA cooperative PRMT5 inhibitor with an IC50 value of 15 nM. PRMT5-IN-47 shows antiproliferative activity. PRMT5-IN-47 shows anticancer activity. | |||||||||||||||||||||
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Keywords