3087291-81-1
3087291-81-1
Chemical Structure
MC-Val-Ala-PAB-NH-Ph-CO-piperidin-4-ol-C4-NH-cyanoguanidine
- CAS No.: 3087291-81-1
- Formula:C49H61N11O9
- Molecular Weight:948.08
InChIKey: YLPGJXSHNIZPKW-CSPRLXHTSA-N
SMILES: O=C(C1=CC=CC(NC(OCC2=CC=C(NC([C@H](C)NC([C@H](C(C)C)NC(CCCCCN3C(C=CC3=O)=O)=O)=O)=O)C=C2)=O)=C1)N4CCC(O)(CC4)CCCCN/C(NC5=CC=CN=C5)=N\C#N
Biological Activity: MC-Val-Ala-PAB-NH-Ph-CO-piperidin-4-ol-C4-NH-cyanoguanidine is a cathepsin B-cleavable linker-payload, with Nampt-IN-22 (HY-187336) as its toxin moiety. MC-Val-Ala-PAB-NH-Ph-CO-piperidin-4-ol-C4-NH-cyanoguanidine can be used for the synthesis of ADC[1].
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MC-Val-Ala-PAB-NH-Ph-CO-piperidin-4-ol-C4-NH-cyanoguanidine | MC-Val-Ala-PAB-NH-Ph-CO-piperidin-4-ol-C4-NH-cyanoguanidine is a cathepsin B-cleavable linker-payload, with Nampt-IN-22 (HY-187336) as its toxin moiety. MC-Val-Ala-PAB-NH-Ph-CO-piperidin-4-ol-C4-NH-cyanoguanidine can be used for the synthesis of ADC. | |||||||||||||||||||||
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References
