3088522-27-1
3088522-27-1
Chemical Structure
KRAS G12C-IN-79
- CAS No.: 3088522-27-1
- Formula:C40H36F4N8O3
- Molecular Weight:752.76
InChIKey: ASCPNKDNBJUKST-KTIQBRJYSA-N
SMILES: [H]C#CC1=C(C=CC2=CC(O)=CC(C3=C(C4=C(C(N([C@@H]5CCN([C@@H]5C)C(/C(F)=C/C6=NN=CC=C6)=O)C)=NC(OC[C@@]78CCCN7C[C@@H](C8)F)=N4)C=N3)F)=C21)F
Biological Activity: KRAS G12C-IN-79 is a KRASG12C inhibitor with an IC50 of 1.9 nM. KRAS G12C-IN-79 functionally inhibits the activity of the GDP-bound form of KRASG12C. KRAS G12C-IN-79 can be used for the research of nonsmall cell lung cancer, colon cancer, pancreatic cancer[1].
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KRAS G12C-IN-79 | KRAS G12C-IN-79 is a KRASG12C inhibitor with an IC50 of 1.9 nM. KRAS G12C-IN-79 functionally inhibits the activity of the GDP-bound form of KRASG12C. KRAS G12C-IN-79 can be used for the research of nonsmall cell lung cancer, colon cancer, pancreatic cancer. | |||||||||||||||||||||
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References
Keywords
