3098824-77-9
Chemical Structure
STEP-IN-1
- CAS No.: 3098824-77-9
- Formula:C21H10ClNO7
- Molecular Weight:423.76
InChIKey: QFKJIIDNPJUCAW-NTEUORMPSA-N
SMILES: O=C(/C1=C/C2=CC=C(O2)C3=CC=C(C=C3Cl)C(O)=O)C4=C(C=CC=C4[N+]([O-])=O)C1=O
Biological Activity: STEP-IN-1 (Compound 14b) is a potent and selective STEP inhibitor with an IC50 of 5.27 μM. STEP-IN-1 has a neuroprotective effect, which can protect nerve cells from glutamate-induced toxicity, reduce cellular ROS accumulation, and inhibit apoptosis. STEP-IN-1 can be used in the study of neurodegenerative diseases[1].
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STEP-IN-1 | STEP-IN-1 (Compound 14b) is a potent and selective STEP inhibitor with an IC50 of 5.27 μM. STEP-IN-1 has a neuroprotective effect, which can protect nerve cells from glutamate-induced toxicity, reduce cellular ROS accumulation, and inhibit apoptosis. STEP-IN-1 can be used in the study of neurodegenerative diseases. | |||||||||||||||||||||
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Keywords