3102130-17-3
Chemical Structure
KRAS G12D-IN-34
- CAS No.: 3102130-17-3
- Formula:C28H27F5N6O2
- Molecular Weight:574.54
InChIKey: DTQYYLFNNCENIH-XDCXBFBSSA-N
SMILES: CC1=C(C(N)=CC(C2=NC3=C(C(NCC4=CN=CC=C4)=C2F)C(N5[C@H]([C@@H](O3)C)[C@H](CC6)N[C@H]6C5)=O)=C1C(F)(F)F)F
Biological Activity: KRAS G12D-IN-34 (Compound 13) is a KRAS (G12D) inhibitor with IC50 values for KRAS (G12D) and KRAS (WT) of 1.05 nM and 1.59 μM respectively. KRAS G12D-IN-34 can be used for research on non-small cell lung cancer[1].
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KRAS G12D-IN-34 | KRAS G12D-IN-34 (Compound 13) is a KRAS (G12D) inhibitor with IC50 values for KRAS (G12D) and KRAS (WT) of 1.05 nM and 1.59 μM respectively. KRAS G12D-IN-34 can be used for research on non-small cell lung cancer. | |||||||||||||||||||||
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Keywords