3105969-17-0
Chemical Structure
EGFR-IN-203
- CAS No.: 3105969-17-0
- Formula:C38H32N4O4
- Molecular Weight:608.69
InChIKey: IVEKFTLYEHMSSL-UHFFFAOYSA-N
SMILES: COC(C1=CC2=C(NC=C2C(C3=CNC4=C3C=C(C=C4)C(OC)=O)C5=CC=C(C=C5)C6NCCC7=C6NC8=CC=CC=C87)C=C1)=O
Biological Activity: EGFR-IN-203 is a EGFR kinase domain inhibitor targeting EGFRT790M/C797S/V948R. EGFR-IN-203 stably binds to the allosteric pocket of EGFR in an inactive conformation. EGFR-IN-203 can be used in research related to cancers such as non-small cell lung cancer[1].
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EGFR-IN-203 | EGFR-IN-203 is a EGFR kinase domain inhibitor targeting EGFRT790M/C797S/V948R. EGFR-IN-203 stably binds to the allosteric pocket of EGFR in an inactive conformation. EGFR-IN-203 can be used in research related to cancers such as non-small cell lung cancer. | |||||||||||||||||||||
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Keywords