3111054-37-3
3111054-37-3
Chemical Structure
PROTAC MLLT1 Degrader-1
- CAS No.: 3111054-37-3
- Formula:C38H38N6O4
- Molecular Weight:642.75
InChIKey: HMRAFGLILOWQBK-KWRHIPAJSA-N
SMILES: O=C(CC1)NC(C1N(C2=O)CC3=C2C=CC=C3C#CCCCCC4=CC=C(C(NC5=NC=C6C=C([C@@H]7N(C)CCC7)NC6=C5)=O)C=C4)=O
Biological Activity: PROTAC MLLT1 Degrader-1 is a PROTAC degrader targeting MLLT1. PROTAC MLLT1 Degrader-1 inhibits AML cell proliferation and viability, suppresses tumor growth in human AML xenograft models, and can block the oncogene transcriptional program. PROTAC MLLT1 Degrader-1 can be used for the research of MLL-rearranged acute myeloid leukemia (AML)[1].
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PROTAC MLLT1 Degrader-1 | PROTAC MLLT1 Degrader-1 is a PROTAC degrader targeting MLLT1. PROTAC MLLT1 Degrader-1 inhibits AML cell proliferation and viability, suppresses tumor growth in human AML xenograft models, and can block the oncogene transcriptional program. PROTAC MLLT1 Degrader-1 can be used for the research of MLL-rearranged acute myeloid leukemia (AML). | |||||||||||||||||||||
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References
Keywords
