3113739-61-7
3113739-61-7
Chemical Structure
SMU-C409
- CAS No.: 3113739-61-7
- Formula:C21H21N3OS2
- Molecular Weight:395.54
InChIKey: AVIBZZBKNUMPRP-UHFFFAOYSA-N
SMILES: CC(C)C(C1=C(NC(NC2=C3C=CC=NC3=CC=C2)=S)SC4=C1CCC4)=O
Biological Activity: SMU-C409 is a TLR1/2 agonist with an EC50 of 65 nM in HEK-Blue hTLR2 Cells. SMU-C409 activates the TLR1/2–MyD88–NF-κB pathway, inducing TNF-α/IL-1β secretion and robust immune cell activation for antitumor immunomodulation. SMU-C409 shows low toxicity in virto. SMU-C409 can be used for cancer immunotherapy research[1].
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SMU-C409 | SMU-C409 is a TLR1/2 agonist with an EC50 of 65 nM in HEK-Blue hTLR2 Cells. SMU-C409 activates the TLR1/2–MyD88–NF-κB pathway, inducing TNF-α/IL-1β secretion and robust immune cell activation for antitumor immunomodulation. SMU-C409 shows low toxicity in virto. SMU-C409 can be used for cancer immunotherapy research. | |||||||||||||||||||||
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References
Keywords
