3116848-78-0

MrgprX2 antagonist-10 Chemical Structure
3116848-78-0

Chemical Structure

MrgprX2 antagonist-10

  • CAS No.: 3116848-78-0
  • Formula:C26H26F2N8O3
  • Molecular Weight:536.53

InChIKey: HPSHDGJTFBLJOX-INIZCTEOSA-N

SMILES: O=C(N1C(C)(CN(CC1)[C@@H](C)C(NC2=NC=C(OC3=C(C=C(C=C3)F)F)N=C2)=O)C)C4=CC5=NC=NN5C=C4

Biological Activity: MrgprX2 antagonist-10 is a potent MRGPRX2 antagonist. MrgprX2 antagonist-10 inhibits MRGPRX2-mediated accumulation and mast cell degranulation (IC50 < 100 nM), thereby blocking mast cell activation. MrgprX2 antagonist-10 can be used in research on MRGPRX2-related inflammatory and allergic diseases[1].

Cat. No. Product Name Purity Description Pricing
HY-185402 		MrgprX2 antagonist-10 98.98% MrgprX2 antagonist-10 is a potent MRGPRX2 antagonist. MrgprX2 antagonist-10 inhibits MRGPRX2-mediated accumulation and mast cell degranulation (IC50 < 100 nM), thereby blocking mast cell activation. MrgprX2 antagonist-10 can be used in research on MRGPRX2-related inflammatory and allergic diseases.
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