312632-55-6
Chemical Structure
MPAM-15
- CAS No.: 312632-55-6
- Formula:C27H27ClO4
- Molecular Weight:450.95
InChIKey: ZEPFMYCUUQVNAO-UHFFFAOYSA-N
SMILES: O=C1C(C(C2=CC=C(C3=CC(Cl)=CC=C3)O2)C4=C(CC(C)(C)CC4=O)O5)=C5CC(C)(C)C1
Biological Activity: MPAM-15 is a blood-brain barrier-penetrant pan-orthosteric allosteric modulator (PAM) of opioid receptors, with ≥16-fold selectivity for μOR over δOR and κOR. MPAM-15 acts as an anti-nociceptive potentiator and analgesic, and its activity is observed in mouse models via both intracerebroventricular and intraperitoneal administration. MPAM-15 is applicable for pain-related research[1].
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MPAM-15 | MPAM-15 is a blood-brain barrier-penetrant pan-orthosteric allosteric modulator (PAM) of opioid receptors, with ≥16-fold selectivity for μOR over δOR and κOR. MPAM-15 acts as an anti-nociceptive potentiator and analgesic, and its activity is observed in mouse models via both intracerebroventricular and intraperitoneal administration. MPAM-15 is applicable for pain-related research. | |||||||||||||||||||||
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Keywords
