31842-01-0
31842-01-0
Chemical Structure
Indoprofen
Synonym(s): (±)-Indoprofe
- CAS. Nr.: 31842-01-0
- Formula:C17H15NO3
- Molecular Weight:281.31
IUPAC Name: 2-(4-(1-oxoisoindolin-2-yl)phenyl)propanoic acid
InChIKey: RJMIEHBSYVWVIN-UHFFFAOYSA-N
SMILES: O=C(O)C(C)C1=CC=C(N(CC2=C3C=CC=C2)C3=O)C=C1
Biological Activity: Indoprofen ((±)-Indoprofe) activates AKT-AMPK signaling pathway, inhibits NF-κB/MAPK signaling pathway. Indoprofen exhibits anti-inflammatory and immunomodulatory activities. Indoprofen is orally active[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Indoprofen | 99.36% | Indoprofen ((±)-Indoprofe) activates AKT-AMPK signaling pathway, inhibits NF-κB/MAPK signaling pathway. Indoprofen exhibits anti-inflammatory and immunomodulatory activities. Indoprofen is orally active. | ||||||||||||||||||||
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Indoprofen (Standard) | ≥98% | Indoprofen (Standard) is the analytical standard of Indoprofen. This product is intended for research and analytical applications. Indoprofen activates AKT-AMPK signaling pathway, inhibits NF-κB/MAPK signaling pathway. Indoprofen exhibits anti-inflammatory and immunomodulatory activities. Indoprofen is orally active. | ||||||||||||||||||||
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References
- [1]. Kim H, Cho SC, Jeong HJ, et al. Indoprofen prevents muscle wasting in aged mice through activation of PDK1/AKT pathway. J Cachexia Sarcopenia Muscle. 2020;11(4):1070-1088. [Content Brief]
- [2]. Bi X, et al., Indoprofen exerts a potent therapeutic effect against sepsis by alleviating high mobility group box 1-mediated inflammatory responses. Toxicol Appl Pharmacol. 2021 Dec 15;433:115778. [Content Brief]
Keywords
