333419-97-9
333419-97-9
Chemical Structure
EGFR T790M/L858R-IN-8
- CAS No.: 333419-97-9
- Formula:C16H11BrN2O3
- Molecular Weight:359.17
InChIKey: UCCUKBQMSKZUOG-UHFFFAOYSA-N
SMILES: O=C(C1=C(O)C2=C(C=CC=C2)NC1=O)NC3=CC(Br)=CC=C3
Biological Activity: EGFR T790M/L858R-IN-8 (Compound 9) is a selective EGFRT790M/L858R mutant kinase inhibitor with a IC50 of 56.8 μM, and it shows no inhibitory activity against wild-type EGFR. EGFR T790M/L858R-IN-8 can be used for the research of non-small cell lung cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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EGFR T790M/L858R-IN-8 | 99.20% | EGFR T790M/L858R-IN-8 (Compound 9) is a selective EGFRT790M/L858R mutant kinase inhibitor with a IC50 of 56.8 μM, and it shows no inhibitory activity against wild-type EGFR. EGFR T790M/L858R-IN-8 can be used for the research of non-small cell lung cancer. | ||||||||||||||||||||
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References
Keywords
