37786-07-5
37786-07-5
Chemical Structure
11-Deoxyprostaglandin F2β
Synonym(s): 11-Deoxy-PGF2β
- CAS No.: 37786-07-5
- Formula:C20H34O4
- Molecular Weight:338.48
IUPAC Name: (Z)-7-((1R,2R,5R)-2-hydroxy-5-((S,E)-3-hydroxyoct-1-en-1-yl)cyclopentyl)hept-5-enoic acid
InChIKey: YRFLKMLJQWGIIZ-LVJWDHJUSA-N
SMILES: OC(CCC/C=C\C[C@@H]1[C@H](CC[C@H]1O)/C=C/[C@@H](O)CCCCC)=O
Biological Activity: 11-Deoxyprostaglandin F2β (11-deoxy PGF2β) is an analog of PGF2β (HY-12956B). PGF2β is a metabolite produced by cyclooxygenase metabolism of arachidonic acid. PGF2β induces dose-dependent release of hexose containing mucin[1][2][3].
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11-Deoxyprostaglandin F2β | 11-Deoxyprostaglandin F2β (11-deoxy PGF2β) is an analog of PGF2β (HY-12956B). PGF2β is a metabolite produced by cyclooxygenase metabolism of arachidonic acid. PGF2β induces dose-dependent release of hexose containing mucin. | |||||||||||||||||||||
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References
- [1]. Mizsak SA, et al. Assignment of 9- and 11- configuration in prostaglandins by CMR. Prostaglandins. 1975 Nov;10(5):807-12. [Content Brief]
- [2]. Lamont JT, et al. Cysteamine and prostaglandin F2 beta stimulate rat gastric mucin release. Gastroenterology. 1983 Feb;84(2):306-13. [Content Brief]
- [3]. Jang Y, et al. Molecular mechanisms underlying the actions of arachidonic acid-derived prostaglandins on peripheral nociception. J Neuroinflammation. 2020 Jan 22;17(1):30. [Content Brief]
Keywords
