380201-24-1
380201-24-1
Chemical Structure
Acetobixan
- CAS No.: 380201-24-1
- Formula:C16H17NO2S
- Molecular Weight:287.38
IUPAC Name: N-(2-methoxybenzyl)-2-(phenylthio)acetamide
InChIKey: IVFWWYCRJNLKNB-UHFFFAOYSA-N
SMILES: O=C(CSC1=CC=CC=C1)NCC2=CC=CC=C2OC
Biological Activity: Acetobixan is an inhibitor of Cellulose Synthase A6 (CESA6). Acetobixan inhibits cellulose components of Pythium insidiosum cell walls. Acetobixan can be used for the research of Pythium insidiosum keratitis[1][2][3][4].
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Acetobixan | Acetobixan is an inhibitor of Cellulose Synthase A6 (CESA6). Acetobixan inhibits cellulose components of Pythium insidiosum cell walls. Acetobixan can be used for the research of Pythium insidiosum keratitis. | |||||||||||||||||||||
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References
- [1]. Gurnani B, et al. Breaking-Down Barriers: Proposal of Using Cellulose Biosynthesis Inhibitors and Cellulase Enzyme as a Novel Treatment Modality for Vision Threatening Pythium Insidiosum Keratitis. Clin Ophthalmol. 2024 Mar 11;18:765-776. [Content Brief]
- [2]. Xia Y, et al. Acetobixan, an inhibitor of cellulose synthesis identified by microbial bioprospecting. PLoS One. 2014 Apr 18;9(4):e95245. [Content Brief]
- [3]. L Lei. Important Regulators of Plant Cellulose Synthesis. The Pennsylvania State University ProQuest Dissertations & Theses, 2015. 10666550.
- [4]. Dietrich H, et al. Inhibitors of Cellulose Biosynthesis. In Modern Crop Protection Compounds (eds P. Jeschke, M. Witschel, W. Krämer and U. Schirmer). 2019.
Keywords
