380351-29-1
380351-29-1
Chemical Structure
EN219
- CAS No.: 380351-29-1
- Formula:C17H13Br2ClN2O
- Molecular Weight:456.56
IUPAC Name: 1-(3,5-bis(4-bromophenyl)-4,5-dihydro-1H-pyrazol-1-yl)-2-chloroethan-1-one
InChIKey: CXRHMHAKZPJNKS-UHFFFAOYSA-N
SMILES: ClCC(N1N=C(C2=CC=C(Br)C=C2)CC1C3=CC=C(Br)C=C3)=O
Biological Activity: EN219 is a moderately selective synthetic covalent ligand against an N-terminal cysteine (C8) of RNF114 with an IC50 of 470 nM. EN219 inhibits RNF114-mediated autoubiquitination and p21 ubiquitination[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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EN219 | 99.21% | EN219 is a moderately selective synthetic covalent ligand against an N-terminal cysteine (C8) of RNF114 with an IC50 of 470 nM. EN219 inhibits RNF114-mediated autoubiquitination and p21 ubiquitination. | ||||||||||||||||||||
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References
Keywords
