459420-09-8
459420-09-8
Chemical Structure
I3MT-3
Synonym(s): HMPSNE
- CAS No.: 459420-09-8
- Formula:C17H14N2O2S
- Molecular Weight:310.37
IUPAC Name: 6-methyl-2-((2-(naphthalen-1-yl)-2-oxoethyl)thio)pyrimidin-4(3H)-one
InChIKey: KKPLVAUVHOSUPR-UHFFFAOYSA-N
SMILES: O=C1NC(SCC(C2=C3C=CC=CC3=CC=C2)=O)=NC(C)=C1
Biological Activity: I3MT-3 (HMPSNE) is a potent, selective, and cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) (IC50=2.7 μM). I3MT-3 is inactive for other H2S/sulfane sulfur-producing enzymes.?I3MT-3 targets a persulfurated cysteine residue located in the active site of 3MST[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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I3MT-3 | 99.76% | I3MT-3 (HMPSNE) is a potent, selective, and cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) (IC50=2.7 μM). I3MT-3 is inactive for other H2S/sulfane sulfur-producing enzymes.?I3MT-3 targets a persulfurated cysteine residue located in the active site of 3MST. | ||||||||||||||||||||
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References
Keywords
