487064-35-7
Chemical Structure
FSH receptor antagonist 1
- CAS No.: 487064-35-7
- Formula:C33H32N2O2
- Molecular Weight:488.62
IUPAC Name: N-(1-acetyl-2,2,4-trimethyl-4-phenyl-1,2,3,4-tetrahydroquinolin-6-yl)-[1,1'-biphenyl]-4-carboxamide
InChIKey: AUNHRXZPYDMERZ-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C2=CC=CC=C2)C=C1)NC3=CC=C4C(C(C)(CC(C)(C)N4C(C)=O)C5=CC=CC=C5)=C3
Biological Activity: FSH receptor antagonist 1 (compound 10) is a potent antagonist of the G(s)-protein-coupled human follicle-stimulating hormone (FSH) receptor. FSH receptor antagonist 1 exhibits an IC50 of 28 nM on a cell line expressing the human FSH receptor. FSH receptor antagonist 1 significantly inhibits follicle growth and ovulation in an ex vivo mouse model[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
FSH receptor antagonist 1 | 95.0% | FSH receptor antagonist 1 (compound 10) is a potent antagonist of the G(s)-protein-coupled human follicle-stimulating hormone (FSH) receptor. FSH receptor antagonist 1 exhibits an IC50 of 28 nM on a cell line expressing the human FSH receptor. FSH receptor antagonist 1 significantly inhibits follicle growth and ovulation in an ex vivo mouse model. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
