509148-73-6
509148-73-6
Chemical Structure
NH2-C2-NH-Boc-d4
Synonym(s): PROTAC Linker 22-d4
- CAS No.: 509148-73-6
- Formula:C7H12D4N2O2
- Molecular Weight:164.24
IUPAC Name: tert-butyl (2-aminoethyl-1,1,2,2-d4)carbamate
InChIKey: AOCSUUGBCMTKJH-CQOLUAMGSA-N
SMILES: O=C(OC(C)(C)C)NC([2H])([2H])C([2H])(N)[2H]
Biological Activity: NH2-C2-NH-Boc-d4 is the deuterium labeled NH2-C2-NH-Boc[1]. NH2-C2-NH-Boc (PROTAC Linker 22) is a alkyl chain-based PROTAC linker can be used in the synthesis of PROTACs[2].
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NH2-C2-NH-Boc-d4 | NH2-C2-NH-Boc-d4 is the deuterium labeled NH2-C2-NH-Boc. NH2-C2-NH-Boc (PROTAC Linker 22) is a alkyl chain-based PROTAC linker can be used in the synthesis of PROTACs. | |||||||||||||||||||||
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NH2-C2-NH-Boc | 99.41% | NH2-C2-NH-Boc (PROTAC Linker 22) is a alkyl chain-based PROTAC linker can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. [Content Brief]
Keywords
