55610-02-1
55610-02-1
Chemical Structure
Cepharadione B
- CAS No.: 55610-02-1
- Formula:C19H15NO4
- Molecular Weight:321.33
IUPAC Name: 1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline-4,5(6H)-dione
InChIKey: AFKGBLKLNRDQFN-UHFFFAOYSA-N
SMILES: O=C1C(N(C)C2=C3C1=CC(OC)=C(OC)C3=C4C(C=CC=C4)=C2)=O
Biological Activity: Cepharadione B (compound 22) is a natural compound isolated from the leaves of Piper sanctum. Cepharadione B is a tyrosinase inhibitor with an IC50 value of 170 μM, and inhibits cell growth in A-549, SK-OV-3, SK-MEL-2, XF-498 and HCT-15 cells[1][2][3].
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Cepharadione B | Cepharadione B (compound 22) is a natural compound isolated from the leaves of Piper sanctum. Cepharadione B is a tyrosinase inhibitor with an IC50 value of 170 μM, and inhibits cell growth in A-549, SK-OV-3, SK-MEL-2, XF-498 and HCT-15 cells. | |||||||||||||||||||||
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References
- [1]. Mata R, et al. Antimycobacterial compounds from Piper sanctum. J Nat Prod. 2004;67(12):1961-1968. [Content Brief]
- [2]. Chou SC, et al. The constituents and their bioactivities of Houttuynia cordata. Chem Pharm Bull (Tokyo). 2009;57(11):1227-1230. [Content Brief]
- [3]. Kim SK, et al. Cytotoxic alkaloids from Houttuynia cordata. Arch Pharm Res. 2001;24(6):518-521. [Content Brief]
Keywords
