570383-98-1
570383-98-1
Chemical Structure
Alloc-Aeg(Fmoc)-OH
- CAS No.: 570383-98-1
- Formula:C23H24N2O6
- Molecular Weight:424.45
InChIKey: JDZYFTKZRREYHE-UHFFFAOYSA-N
SMILES: O=C(NCCN(CC(O)=O)C(OCC=C)=O)OCC1C2=C(C3=C1C=CC=C3)C=CC=C2
Biological Activity: Alloc-Aeg (Fmoc)-OH is a protected serine triphosphate building block and an Nα-Fmoc protected amino acid. Alloc-Aeg (Fmoc)-OH contains serine protected by α-N-allyloxycarbonyl (Alloc) and bis (allyl) phosphate groups, and it can be used in the synthesis of peptide nucleic acids (PNAs). Alloc-Aeg (Fmoc)-OH is applicable to research related to Alzheimer's disease[1][2].
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Alloc-Aeg(Fmoc)-OH | Alloc-Aeg (Fmoc)-OH is a protected serine triphosphate building block and an Nα-Fmoc protected amino acid. Alloc-Aeg (Fmoc)-OH contains serine protected by α-N-allyloxycarbonyl (Alloc) and bis (allyl) phosphate groups, and it can be used in the synthesis of peptide nucleic acids (PNAs). Alloc-Aeg (Fmoc)-OH is applicable to research related to Alzheimer's disease. | |||||||||||||||||||||
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References
- [1]. Shapiro G, et al. Combined Fmoc-Alloc strategy for a general SPPS of phosphoserine peptides; preparation of phosphorylation-dependent tau antisera. Bioorg Med Chem. 1997;5(1):147-156. [Content Brief]
- [2]. Tomassi S, Montalban F F, Russo R, et al. Investigation of the stereochemical-dependent DNA and RNA binding of arginine-based nucleopeptides[J]. Symmetry, 2019, 11(4): 567.
