60207-90-1
60207-90-1
Chemical Structure
Propiconazole
- CAS No.: 60207-90-1
- Formula:C15H17Cl2N3O2
- Molecular Weight:342.22
IUPAC Name: 1-((2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl)methyl)-1H-1,2,4-triazole
InChIKey: STJLVHWMYQXCPB-UHFFFAOYSA-N
SMILES: CCCC1OC(CN2N=CN=C2)(C3=CC=C(Cl)C=C3Cl)OC1
Biological Activity: Propiconazole is an orally active N-substituted triazole used as a fungicide. Propiconazole is a mouse liver hepatotoxicant and a hepatocarcinogen that has adverse reproductive and developmental toxicities in experimental animals[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Propiconazole | 98.56% | Propiconazole is an orally active N-substituted triazole used as a fungicide. Propiconazole is a mouse liver hepatotoxicant and a hepatocarcinogen that has adverse reproductive and developmental toxicities in experimental animals. | ||||||||||||||||||||
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Propiconazole (Standard) | 98.53% | Propiconazole (Standard) is the analytical standard of Propiconazole. This product is intended for research and analytical applications. Propiconazole is an orally active N-substituted triazole used as a fungicide. Propiconazole is a mouse liver hepatotoxicant and a hepatocarcinogen that has adverse reproductive and developmental toxicities in experimental animals. | ||||||||||||||||||||
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Propiconazole-d3 nitrate | Propiconazole-d3 (nitrate) is the deuterium labeled Propiconazole nitrate. Propiconazole is a broad-spectrum triazole fungicide that inhibits the conversion of lanosterol to ergosterol, leading to fungal cell membrane disruption. Propiconazole inhibits S. cerevisiae, but not rat liver, microsomal cytochrome P450 (IC50s=0.04 and >200 µM, respectively). Propiconazole inhibits the growth of T. deformans and R. stolonifer (ED50s=0.073 and 4.6 µg/mL, respectively). Propiconazole increases production of reactive oxygen species (ROS). | |||||||||||||||||||||
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Propiconazole-d7 | Propiconazole-d7 is the deuterium labeled Propiconazole. Propiconazole is a broad-spectrum triazole fungicide that inhibits the conversion of lanosterol to ergosterol, leading to fungal cell membrane disruption. Propiconazole inhibits S. cerevisiae, but not rat liver, microsomal cytochrome P450 (IC50s=0.04 and >200 μM, respectively). Propiconazole inhibits the growth of T. deformans and R. stolonifer (ED50s=0.073 and 4.6 μg/mL, respectively). Propiconazole increases production of reactive oxygen species (ROS). | |||||||||||||||||||||
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References
- [1]. Guobin Sun, et al. Propiconazole-induced cytochrome P450 gene expression and enzymatic activities in rat and mouse liver. Toxicol Lett. 2005 Feb 15;155(2):277-87. [Content Brief]
- [2]. ShuangLi, et al. Single and Combined Cytotoxicity Research of Propiconazole and Nano-zinc Oxide on the NIH/3T3 Cell. Procedia Environmental Sciences Volume 18, 2013, Pages 100-105.
