636564-27-7
Chemical Structure
CC-410
- CAS No.: 636564-27-7
- Formula:C27H46N2O4
- Molecular Weight:462.67
InChIKey: XMULAOLMWUSMLQ-FZMDYVDPSA-N
SMILES: N[C@H]1[C@@]2([H])[C@@]3([H])[C@@]([C@@](CC3)([H])[C@H](C)CCC(OC)=O)([C@H](C[C@]2([H])[C@@]4([C@](C[C@@H](CC4)OC(C)=O)([H])C1)C)N)C
Biological Activity: CC-410 is a selective Nicotinamide N-methyltransferase (NNMT) inhibitor with a human IC50 value of 1.6 µM. CC-410 impairs terminal adipocyte differentiation via glucocorticoid signaling network deregulation, inhibits adipogenesis and lipid accumulation with time-sensitive activity limited to early adipogenesis stages. CC-410 can be used for the researches of early-onset obesity, glucocorticoid-induced obesity[1].
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CC-410 | CC-410 is a selective Nicotinamide N-methyltransferase (NNMT) inhibitor with a human IC50 value of 1.6 µM. CC-410 impairs terminal adipocyte differentiation via glucocorticoid signaling network deregulation, inhibits adipogenesis and lipid accumulation with time-sensitive activity limited to early adipogenesis stages. CC-410 can be used for the researches of early-onset obesity, glucocorticoid-induced obesity. | |||||||||||||||||||||
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Keywords
