66067-26-3
Chemical Structure
Licoisoflavanone
- CAS No.: 66067-26-3
- Formula:C20H18O6
- Molecular Weight:354.35
IUPAC Name: 5,7-dihydroxy-3-(5-hydroxy-2,2-dimethyl-2H-chromen-6-yl)chroman-4-one
InChIKey: JNDPLDZUOFZXIG-UHFFFAOYSA-N
SMILES: O=C1C(C2=CC=C3C(C=CC(C)(C)O3)=C2O)COC4=CC(O)=CC(O)=C14
Biological Activity:
Licoisoflavanone is an orally active isoflavane-based immunomodulator with multiple activities including antiviral, anti-inflammatory, cytoprotective and cancer cell apoptosis-inducing effects. Licoisoflavanone can be isolated from the roots and rhizomes of Glycyrrhiza uralensis Fisch. Licoisoflavanone not only enhances the body's immunity, but also effectively prevents acute respiratory distress syndrome and multiple organ damage by alleviating cytokine storm, thereby reducing the degree of inflammation. In rats, Licoisoflavanone undergoes multiple metabolic transformation processes such as glucuronidation, hydroxylation, sulfation, methylation and dehydrogenation. Licoisoflavanone has become an important candidate molecule for research on COVID-19 and related inflammatory diseases[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Licoisoflavanone | 96.74% | Licoisoflavanone is an orally active isoflavane-based immunomodulator with multiple activities including antiviral, anti-inflammatory, cytoprotective and cancer cell apoptosis-inducing effects. Licoisoflavanone can be isolated from the roots and rhizomes of Glycyrrhiza uralensis Fisch. Licoisoflavanone not only enhances the body's immunity, but also effectively prevents acute respiratory distress syndrome and multiple organ damage by alleviating cytokine storm, thereby reducing the degree of inflammation. In rats, Licoisoflavanone undergoes multiple metabolic transformation processes such as glucuronidation, hydroxylation, sulfation, methylation and dehydrogenation. Licoisoflavanone has become an important candidate molecule for research on COVID-19 and related inflammatory diseases. |
||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Li yanhua, et al. CN113262246A. 2021-04-19.
- [2]. Wang Q, et al. Metabolites identification of bioactive licorice compounds in rats. J Pharm Biomed Anal. 2015;115:515-522. [Content Brief]
- [3]. Li xin, et al. CN103989736A. 2014-06-16.
- [4]. Fu Y, et al. Deep learning-based network pharmacology for exploring the mechanism of licorice for the treatment of COVID-19. Sci Rep. 2023;13(1):5844. Published 2023 Apr 10. [Content Brief]
Keywords
