72517-81-8
Chemical Structure
9,11-Methane-epoxy prostaglandin F1α
Synonym(s): 9,11-Epoxymethano PGH1; 9,11-methane-epoxy PGF1α
- CAS No.: 72517-81-8
- Formula:C21H36O4
- Molecular Weight:352.51
IUPAC Name: 7-((5S,6R)-6-((S,E)-3-hydroxyoct-1-en-1-yl)-2-oxabicyclo[2.2.1]heptan-5-yl)heptanoic acid
InChIKey: VGRVXLWYKKBTNM-KQMLLPOFSA-N
SMILES: OC(CCCCCC[C@H]1[C@@H]([C@]2([H])C[C@@]1([H])CO2)/C=C/[C@H](O)CCCCC)=O
Biological Activity: 9,11-methane-epoxy Prostaglandin F1α (9,11-Epoxymethano PGH1; 9,11-methane-epoxy PGF1α) is a derivative of prostaglandin H1. 9,11-methane-epoxy Prostaglandin F1α induces aggregation of isolated rabbit platelets (EC50=0.88 µM) and contraction of rabbit aortic strips (EC50=0.11 µM). 9,11-methane-epoxy Prostaglandin F1α induces contraction of isolated guinea pig tracheas (EC50 = 3.4 µM)[1].
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9,11-Methane-epoxy prostaglandin F1α | 9,11-methane-epoxy Prostaglandin F1α (9,11-Epoxymethano PGH1; 9,11-methane-epoxy PGF1α) is a derivative of prostaglandin H1. 9,11-methane-epoxy Prostaglandin F1α induces aggregation of isolated rabbit platelets (EC50=0.88 µM) and contraction of rabbit aortic strips (EC50=0.11 µM). 9,11-methane-epoxy Prostaglandin F1α induces contraction of isolated guinea pig tracheas (EC50 = 3.4 µM). | |||||||||||||||||||||
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Keywords
