817623-11-3
Chemical Structure
5'-DMTr-2,2'-anhydrothymidine
- CAS No.: 817623-11-3
- Formula:C31H30N2O7
- Molecular Weight:542.58
IUPAC Name: (2R,3R,3aS,9aR)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-hydroxy-7-methyl-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one
InChIKey: BQEQCEZNLIKSSH-CITHKVLSSA-N
SMILES: O[C@H]1[C@H](OC2=NC3=O)[C@H](N2C=C3C)O[C@@H]1COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6
Biological Activity: 5'-DMTr-2,2'-anhydrothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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5'-DMTr-2,2'-anhydrothymidine | 5'-DMTr-2,2'-anhydrothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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Keywords
