845272-21-1
845272-21-1
Chemical Structure
Varlitinib
Synonym(s): ASLAN001; ARRY-334543
- CAS No.: 845272-21-1
- Formula:C22H19ClN6O2S
- Molecular Weight:466.94
IUPAC Name: (R)-N4-(3-chloro-4-(thiazol-2-ylmethoxy)phenyl)-N6-(4-methyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine
InChIKey: UWXSAYUXVSFDBQ-CYBMUJFWSA-N
SMILES: C[C@H]1N=C(NC2=CC3=C(NC4=CC=C(OCC5=NC=CS5)C(Cl)=C4)N=CN=C3C=C2)OC1
Biological Activity: Varlitinib (ASLAN001) is a potent, reversible, small molecule pan-EGFR inhibitor with IC50s of 7, 2, 4 nM for HER1, HER2 and HER4, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Varlitinib | 98.66% | Varlitinib (ASLAN001) is a potent, reversible, small molecule pan-EGFR inhibitor with IC50s of 7, 2, 4 nM for HER1, HER2 and HER4, respectively. | ||||||||||||||||||||
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Varlitinib (Standard) | ≥98% | Varlitinib (Standard) is the analytical standard of Varlitinib (HY-10530). This product is intended for research and analytical applications. Varlitinib (ASLAN001) is a potent, reversible, small molecule pan-EGFR inhibitor with IC50s of 7, 2, 4 nM for HER1, HER2 and HER4, respectively. | ||||||||||||||||||||
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References
Keywords
