850033-84-0
850033-84-0
Chemical Structure
5-HT2C agonist-13
- CAS No.: 850033-84-0
- Formula:C14H15F3N2O
- Molecular Weight:284.28
InChIKey: AZBGLEQDAYJKBP-NSHDSACASA-N
SMILES: FC(F)(C1=C2C([C@@]3([H])N(CCNC3)C2=O)=CC(CC)=C1)F
Biological Activity: 5-HT2C agonist-13 is an orally active, selective and brain-penetrant 5-HT2C receptor agonist with human 5-HT2C receptor EC50 of 16 nM, Ki of 20 nM. 5-HT2C agonist-13 functionally activates 5-HT2C receptors, reduces food intake, reduces body weight gain, and exhibits effects reversible by a selective 5-HT2C antagonist. 5-HT2C agonist-13 can be used for the research of obesity[1].
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5-HT2C agonist-13 | 5-HT2C agonist-13 is an orally active, selective and brain-penetrant 5-HT2C receptor agonist with human 5-HT2C receptor EC50 of 16 nM, Ki of 20 nM. 5-HT2C agonist-13 functionally activates 5-HT2C receptors, reduces food intake, reduces body weight gain, and exhibits effects reversible by a selective 5-HT2C antagonist. 5-HT2C agonist-13 can be used for the research of obesity. | |||||||||||||||||||||
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References
Keywords
