85081-18-1
85081-18-1
Chemical Structure
NBI-98782
Synonym(s): (+)-DTBZ;(+)-α-Dihydrotetrabenazine;(+)-α-DHTBZ
- CAS No.: 85081-18-1
- Formula:C19H29NO3
- Molecular Weight:319.44
IUPAC Name: (2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol
InChIKey: WEQLWGNDNRARGE-DJIMGWMZSA-N
SMILES: COC(C=C1CCN2C[C@@H](CC(C)C)[C@@H]3O)=C(C=C1[C@]2(C3)[H])OC
Biological Activity: NBI-98782 is a high affinity and selectivity vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki of 3 nM. NBI-98782 has antipsychotic activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NBI-98782 | 98.56% | NBI-98782 is a high affinity and selectivity vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki of 3 nM. NBI-98782 has antipsychotic activity. | ||||||||||||||||||||
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References
- [1]. Huang M, et al. Effects of NBI-98782, a selective vesicular monoamine transporter 2 (VMAT2) inhibitor, on neurotransmitter efflux and phencyclidine-induced locomotor activity: Relevance to tardive dyskinesia and antipsychotic action. Pharmacol Biochem Behav. 2020 Mar;190:172872. [Content Brief]
Keywords
