851030-08-5
851030-08-5
Chemical Structure
2,3-Dinor-11β-prostaglandin F2α-d9
Synonym(s): 2,3-Dinor-11β-PGF2α-d9, 2,3-dinor-11-epi PGF2α-d9
- CAS No.: 851030-08-5
- Formula:C18H21D9O5
- Molecular Weight:335.48
IUPAC Name: (Z)-5-((1R,2R,3S,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl-5,5,6,6,7,7,8,8,8-d9)cyclopentyl)pent-3-enoic acid
InChIKey: IDKLJIUIJUVJNR-RJGNUDNQSA-N
SMILES: O[C@@H]1[C@@H]([C@H]([C@H](C1)O)/C=C/[C@H](CC([2H])(C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])[2H])O)C/C=C\CC(O)=O
Biological Activity: 2,3-Dinor-11β-prostaglandin F2α-d9 is the deuterium labeled 2,3-Dinor-11β-prostaglandin F2α[1].
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2,3-Dinor-11β-prostaglandin F2α-d9 | 2,3-Dinor-11β-prostaglandin F2α-d9 is the deuterium labeled 2,3-Dinor-11β-prostaglandin F2α. | |||||||||||||||||||||
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2,3-Dinor-11beta-prostaglandin F2alpha | 2,3-Dinor-11beta-prostaglandin F2alpha (2,3-Dinor-11β-PGF2α) is a metabolite of PGD2. Urinary excretion of 2,3-Dinor-11beta-prostaglandin F2alpha is increased in patients with mast cell activation disease (MCAD) and has been used as a marker of increased PGD2 levels. 2,3-Dinor-11beta-prostaglandin F2alpha levels are also increased in the urine of patients with asthma and are positively correlated with impaired lung function. | |||||||||||||||||||||
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