862719-04-8
862719-04-8
Chemical Structure
LDHA-IN-9
- CAS 番号: 862719-04-8
- Formula:C17H22BrNO4
- Molecular Weight:384.26
InChIKey: LNJDVRYHCQLOSZ-UHFFFAOYSA-N
SMILES: BrC1=C2C(N(O)C(C(OC)=O)=C2COCCCCCC)=CC=C1
Biological Activity: LDHA-IN-9 (Compound 1g) is an inhibitor for LDH-A with an IC50 of 25 nM. LDHA-IN-9 inhibits the proliferation of DLD-1 cell (GI50 of 27 μM) through apoptosis induction. LDHA-IN-9 exhibits antitumor activity in mouse model without significant toxicity (25 mg/kg)[1].
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LDHA-IN-9 | LDHA-IN-9 (Compound 1g) is an inhibitor for LDH-A with an IC50 of 25 nM. LDHA-IN-9 inhibits the proliferation of DLD-1 cell (GI50 of 27 μM) through apoptosis induction. LDHA-IN-9 exhibits antitumor activity in mouse model without significant toxicity (25 mg/kg). | |||||||||||||||||||||
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References
Keywords
