87051-46-5
Chemical Structure
Butanserin
Synonym(s): R 53393
- CAS No.: 87051-46-5
- Formula:C24H26FN3O3
- Molecular Weight:423.48
IUPAC Name: 3-(4-(4-(4-fluorobenzoyl)piperidin-1-yl)butyl)quinazoline-2,4(1H,3H)-dione
InChIKey: MLDQSYUQSLUEPG-UHFFFAOYSA-N
SMILES: O=C(N1CCCCN2CCC(C(C3=CC=C(F)C=C3)=O)CC2)C4=CC=CC=C4NC1=O
Biological Activity: Butanserin (R 53393) is a potent and selective α1-adrenoceptor antagonist for the study of cardiovascular disease[1].
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Butanserin | Butanserin (R 53393) is a potent and selective α1-adrenoceptor antagonist for the study of cardiovascular disease. | |||||||||||||||||||||
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- [1]. Korstanje C, et al. Characterization of flufylline, fluprofylline, ritanserin, butanserin and R 56413 with respect to in-vivo alpha 1-,alpha 2- and 5-HT2-receptor antagonism and in-vitro affinity for alpha 1-,alpha 2- and 5-HT2-receptors: comparison with ketanserin. J Pharm Pharmacol. 1986 May;38(5):374-9. [Content Brief]
Keywords