876755-27-0
876755-27-0
Chemical Structure
RO 4927350
- CAS No.: 876755-27-0
- Formula:C27H28N4O6S
- Molecular Weight:536.60
IUPAC Name: (2S,3S)-2-((R)-4-(4-(2-hydroxyethoxy)phenyl)-2,5-dioxoimidazolidin-1-yl)-3-phenyl-N-(4-propionylthiazol-2-yl)butanamide
InChIKey: RKKBPPTYPGTSEA-FNVCAUGXSA-N
SMILES: C[C@@H](C1=CC=CC=C1)[C@H](N2C([C@@H](C3=CC=C(C=C3)OCCO)NC2=O)=O)C(NC4=NC(C(CC)=O)=CS4)=O
Biological Activity: RO 4927350 is a potent and selective non-ATP-competitive MEK1/2 inhibitor. RO 4927350 exhibits significant antitumor efficacy in a broad spectrum of tumor models[1].
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RO 4927350 | RO 4927350 is a potent and selective non-ATP-competitive MEK1/2 inhibitor. RO 4927350 exhibits significant antitumor efficacy in a broad spectrum of tumor models. | |||||||||||||||||||||
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References
Keywords
