885060-09-3
885060-09-3
Chemical Structure
Filanesib
Synonym(s): ARRY-520
- CAS No.: 885060-09-3
- Formula:C20H22F2N4O2S
- Molecular Weight:420.48
IUPAC Name: (S)-2-(3-aminopropyl)-5-(2,5-difluorophenyl)-N-methoxy-N-methyl-2-phenyl-1,3,4-thiadiazole-3(2H)-carboxamide
InChIKey: LLXISKGBWFTGEI-FQEVSTJZSA-N
SMILES: O=C(N1[C@@](C2=CC=CC=C2)(CCCN)SC(C3=CC(F)=CC=C3F)=N1)N(OC)C
Biological Activity: Filanesib (ARRY-520) is a selective and noncompetitive kinesin spindle protein (KSP) inhibitor, with an IC50 of 6 nM for human KSP. Filanesib induces cell death by apoptosis in vitro. Filanesib has potent anti-proliferative activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Filanesib | 99.59% | Filanesib (ARRY-520) is a selective and noncompetitive kinesin spindle protein (KSP) inhibitor, with an IC50 of 6 nM for human KSP. Filanesib induces cell death by apoptosis in vitro. Filanesib has potent anti-proliferative activity. | ||||||||||||||||||||
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References
Keywords
