89197-00-2
89197-00-2
Chemical Structure
Efaroxan hydrochloride
- CAS No.: 89197-00-2
- Formula:C13H17ClN2O
- Molecular Weight:252.74
IUPAC Name: 2-(2-ethyl-2,3-dihydrobenzofuran-2-yl)-4,5-dihydro-1H-imidazole hydrochloride
InChIKey: DWOIUCRHVWIHAH-UHFFFAOYSA-N
SMILES: CCC1(C2=NCCN2)OC3=CC=CC=C3C1.[H]Cl
Biological Activity: Efaroxan hydrochloride is a potent, selective and orally active α2-adrenoceptor antagonist, with antidiabetic activity. Efaroxan hydrochloride is a selective I1-Imidazoline receptor antagonist. Efaroxan hydrochloride can be used for the research of cardiovascular disease[1][2][3].
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Efaroxan hydrochloride | 99.80% | Efaroxan hydrochloride is a potent, selective and orally active α2-adrenoceptor antagonist, with antidiabetic activity. Efaroxan hydrochloride is a selective I1-Imidazoline receptor antagonist. Efaroxan hydrochloride can be used for the research of cardiovascular disease. | ||||||||||||||||||||
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Efaroxan hydrochloride (Standard) | ≥98% | Efaroxan (hydrochloride) (Standard) is the analytical standard of Efaroxan (hydrochloride). This product is intended for research and analytical applications. Efaroxan hydrochloride is a potent, selective and orally active α2-adrenoceptor antagonist, with antidiabetic activity. Efaroxan hydrochloride is a selective I1-Imidazoline receptor antagonist. Efaroxan hydrochloride can be used for the research of cardiovascular disease. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-B1416Efaroxan -
Similarity Score 0.63
HY-103197R2-Methoxyidazoxan monohydrochloride (Standard) -
Similarity Score 0.63
HY-127112-Methoxyidazoxan -
Similarity Score 0.61
HY-101300RCirazoline hydrochloride (Standard) -
Similarity Score 0.61
HY-14561AIdazoxan hydrochloride -
Similarity Score 0.60
HY-113985Cirazoline -
Similarity Score 0.59
HY-128045Fenoxazoline -
Similarity Score 0.58
HY-W982195Napamezole hydrochloride -
Similarity Score 0.57
HY-B0556ATetrahydrozoline hydrochloride -
Explore the MedChemAI to find more analogs
References
- [1]. Berridge TL, et al. Selectivity profile of the alpha 2-adrenoceptor antagonist efaroxan in relation to plasma glucose and insulin levels in the rat. Eur J Pharmacol. 1992 Mar 24;213(2):205-12. [Content Brief]
- [2]. T L Berridge, et al. Selectivity profile of the alpha 2-adrenoceptor antagonist efaroxan in relation to plasma glucose and insulin levels in the rat. Eur J Pharmacol. 1992 Mar 24;213(2):205-12.
- [3]. A O Abdel-Zaher, et al. The potential antidiabetic activity of some alpha-2 adrenoceptor antagonists. Pharmacol Res. 2001 Nov;44(5):397-409. [Content Brief]
