892407-39-5
Chemical Structure
JNJ-28583867
- CAS No.: 892407-39-5
- Formula:C24H32N2O2S
- Molecular Weight:412.59
IUPAC Name: (S)-4-(3-((2-methyl-4-(4-(methylthio)phenyl)-1,2,3,4-tetrahydroisoquinolin-7-yl)oxy)propyl)morpholine
InChIKey: XYYGFCDTBHAUSN-DEOSSOPVSA-N
SMILES: CSC1=CC=C([C@@H]2CN(C)CC3=C2C=CC(OCCCN4CCOCC4)=C3)C=C1
Biological Activity: JNJ-28583867 is an orally active and selective histamine H3 receptor antagonist (Ki=10.6 nM) and serotonin transporter (SERT) inhibitor (Ki=3.7 nM). JNJ-28583867 can be used in the research of depression[1].
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JNJ-28583867 | JNJ-28583867 is an orally active and selective histamine H3 receptor antagonist (Ki=10.6 nM) and serotonin transporter (SERT) inhibitor (Ki=3.7 nM). JNJ-28583867 can be used in the research of depression. | |||||||||||||||||||||
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Keywords