905854-03-7
Chemical Structure
(3S,4S)-Tivantinib
Synonym(s): (3S,4S)-ARQ 197; ARQ 198
- CAS No.: 905854-03-7
- Formula:C23H19N3O2
- Molecular Weight:369.42
IUPAC Name: (3S,4S)-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione
InChIKey: UCEQXRCJXIVODC-WOJBJXKFSA-N
SMILES: O=C(N1)[C@@H]([C@H](C1=O)C2=CNC3=C2C=CC=C3)C4=CN5CCCC6=C5C4=CC=C6
Biological Activity: (3S,4S)-Tivantinib is a potent and highly selective inhibitor of the receptor tyrosine kinase c-MET. (3S,4S)-Tivantinib has two novel targets, GSK3α and GSK3β, which play an important role in the cellular mechanism of non-small cell lung cancer (NSCLC)[1].
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(3S,4S)-Tivantinib | 98.71% | (3S,4S)-Tivantinib is a potent and highly selective inhibitor of the receptor tyrosine kinase c-MET. (3S,4S)-Tivantinib has two novel targets, GSK3α and GSK3β, which play an important role in the cellular mechanism of non-small cell lung cancer (NSCLC). | ||||||||||||||||||||
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Keywords
