916214-57-8
916214-57-8
Chemical Structure
Nelonemdaz potassium
Synonym(s): Salfaprodil; Neu2000 potassium
- CAS No.: 916214-57-8
- Formula:C15H7F7KNO3
- Molecular Weight:421.31
IUPAC Name: potassium 2-hydroxy-5-((2,3,5,6-tetrafluoro-4-(trifluoromethyl)benzyl)amino)benzoate
InChIKey: KLOANMLPWLPVSW-UHFFFAOYSA-M
SMILES: OC1=CC=C(C=C1C(O[K])=O)NCC2=C(C(F)=C(C(F)=C2F)C(F)(F)F)F
Biological Activity: Nelonemdaz (Salfaprodil) potassium is an NR2B-selective and uncompetitive antagonist of N-methyl-D-aspartate (NMDA). Nelonemdaz potassium is also a free radical scavenger. Nelonemdaz potassium has excellent neuroprotection against NMDA- and free radical-induced cell death[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Nelonemdaz potassium | 99.86% | Nelonemdaz (Salfaprodil) potassium is an NR2B-selective and uncompetitive antagonist of N-methyl-D-aspartate (NMDA). Nelonemdaz potassium is also a free radical scavenger. Nelonemdaz potassium has excellent neuroprotection against NMDA- and free radical-induced cell death. | ||||||||||||||||||||
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Nelonemdaz potassium (Standard) | ≥98% | Nelonemdaz potassium (Standard) is the analytical standard of Nelonemdaz potassium (HY-106408A). This product is intended for research and analytical applications. Nelonemdaz (Salfaprodil) potassium is an NR2B-selective and uncompetitive antagonist of N-methyl-D-aspartate (NMDA). Nelonemdaz potassium is also a free radical scavenger. Nelonemdaz potassium has excellent neuroprotection against NMDA- and free radical-induced cell death. | ||||||||||||||||||||
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References
- [1]. Gwag BJ, et al. Marked prevention of ischemic brain injury by Neu2000, an NMDA antagonist and antioxidant derived from aspirin and sulfasalazine. J Cereb Blood Flow Metab. 2007 Jun;27(6):1142-51. [Content Brief]
- [2]. Sung IC, et, al. Neu2000, an NR2B-selective, Moderate NMDA Receptor Antagonist and Potent Spin Trapping Molecule for Stroke. Drug News Perspect. 2010 Nov; 23(9): 549-56. [Content Brief]
