917393-39-6
917393-39-6
Chemical Structure
Lorediplon
- CAS No.: 917393-39-6
- Formula:C20H15FN4O2S
- Molecular Weight:394.42
IUPAC Name: N-(2-fluoro-5-(3-(thiophene-2-carbonyl)pyrazolo[1,5-a]pyrimidin-7-yl)phenyl)-N-methylacetamide
InChIKey: NQPOCLFSADOXBR-UHFFFAOYSA-N
SMILES: CC(N(C1=CC(C2=CC=NC3=C(C(C4=CC=CS4)=O)C=NN23)=CC=C1F)C)=O
Biological Activity:
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Lorediplon | 99.88% | Lorediplon is a novel non-benzodiazepine drug acting as a GABAA receptor modulator, differentially active at the alpha1-subunit, associated with promoting sleep. | ||||||||||||||||||||
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References
- Zisapel N. Current Phase II investigational therapies for insomnia. Expert Opin Investig Drugs. 2015 Mar;24(3):401-411. [Content Brief]
- Horoszok L, et al. A single-dose, randomized, double-blind, double dummy, placebo and positive-controlled, five-way cross-over study to assess the pharmacodynamic effects of lorediplon in a phase advance model of insomnia in healthy Caucasian adult male subjects. Hum Psychopharmacol. 2014 May;29(3):266-273. [Content Brief]
Keywords
