926906-64-1
Chemical Structure
VRX0466617
- CAS No.: 926906-64-1
- Formula:C19H20BrN5O2S
- Molecular Weight:462.36
IUPAC Name: 5-((4-((4-bromophenyl)amino)phenyl)amino)-N-(1-hydroxypropan-2-yl)-3-oxo-2,3-dihydroisothiazole-4-carboximidamide
InChIKey: YFQDMCVTQPZMAQ-UHFFFAOYSA-N
SMILES: OCC(C)NC(C(C(NS1)=O)=C1NC2=CC=C(NC3=CC=C(Br)C=C3)C=C2)=N
Biological Activity: VRX0466617 is a selective and ATP-competitive Chk2 inhibitor with an IC50 of 120 nM and a Ki of 11 nM. VRX0466617 does not inhibit the related Chk1 activity. VRX0466617 can be used in the study of cancer.
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VRX0466617 | 99.91% | VRX0466617 is a selective and ATP-competitive Chk2 inhibitor with an IC50 of 120 nM and a Ki of 11 nM. VRX0466617 does not inhibit the related Chk1 activity. VRX0466617 can be used in the study of cancer. | ||||||||||||||||||||
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Keywords