92693-02-2
92693-02-2
Chemical Structure
15(S)-HETRE
- CAS No.: 92693-02-2
- Formula:C20H34O3
- Molecular Weight:322.48
IUPAC Name: (R,8Z,11Z,13E)-15-hydroxyicosa-8,11,13-trienoic acid
InChIKey: IUKXMNDGTWTNTP-IPNUHODOSA-N
SMILES: CCCCC[C@H](/C=C/C=C\C/C=C\CCCCCCC(O)=O)O
Biological Activity: 15(S)-HETRE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of dihomo-γ-linolenic acid. It is an inhibitor of 5-LO in human PMNL with an IC50 value of 4.6 μM. In RBL cells, 15(S)-HETrE inhibits 5-LO, but is about 1/20 as potent as 15(S)-HpETE.
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15(S)-HETRE | 99.0% | 15(S)-HETRE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of dihomo-γ-linolenic acid. It is an inhibitor of 5-LO in human PMNL with an IC50 value of 4.6 μM. In RBL cells, 15(S)-HETrE inhibits 5-LO, but is about 1/20 as potent as 15(S)-HpETE. | ||||||||||||||||||||
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Keywords
